AQP9

Gene Information
 
Gene Symbol
AQP9
 
Aliases
AQP-9, HsT17287, SSC1
 
Entrez Gene ID
366
 
Gene Name
Aquaporin 9
 
Chromosomal Location
15q
 
HGNC ID
643
 
Summary
The aquaporins are a family of water-selective membrane channels. The protein encoded by this gene allows passage of a wide variety of noncharged solutes. It stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. (provided by RefSeq)
 
GeneCards ID
 
UniGene
 
RefSeq DNA
 
RefSeq mRNA
  e!Ensembl
Gene
Transcript  
Protein

Gene Ontology (GO)

GO ID Ontology Definition Evidence Reference
GO:0006810 Biological process Transport TAS 9733774
GO:0006863 Biological process Purine base transport IDA 9733774
GO:0006955 Biological process Immune response TAS 9514918
GO:0006970 Biological process Response to osmotic stress TAS 9733774
GO:0007588 Biological process Excretion TAS 9733774
Protein Information
 
Protein Name
Aquaporin-9
 
Function
Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol
 
Refseq Proteins
 
UniProt
 
InterPro
 
Pfam
Pfam Accession Pfam ID
PF00230 MIP Major intrinsic protein
 
KEGG
 
OMIM
 
Interactions
STRING MINT I2D

Associated Diseases

Diseases References
Edema 20126625
   
References
 
Primary:

[Expression of aquaporin 9 in granulosa cells of patients with polycystic ovary syndrome in IVF-cycles].

Lu Xiu-e, Qian Yu-li, Huang He-feng
The Affiliated Obstetrics and Gynecology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2007 Sep;36(5):449-53.

 

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